MGI launches new nanopore sequencing products with advanced CycloneSEQ technology

A group photo of members on the SEQ ALL Alliance Launch Ceremony. File photo

MGI Tech Co., (“MGI”), a company committed to building core tools and technologies that drive innovation in life science, announced yesterday two new sequencing products CycloneSEQ-WT02* and CycloneSEQ-WY01*. 

CycloneSEQ-WT02

CycloneSEQ-WY01

With potential across different areas of genomics, CycloneSEQ™ technology integrates numerous technological improvements, including advanced protein engineering, a novel flow cell design, and a cutting-edge base calling algorithm, to enable high accuracy and throughput in sequencing.

“By integrating CycloneSEQ™ nanopore sequencing with our proprietary DNBSEQ™ sequencing technology, we are excited to further expand our omics technologies portfolio,” said Duncan Yu, president of MGI.

“This advancement allows us to provide MGI partners and customers worldwide with a full suite of omics capabilities across diverse range of sequencing throughputs and read lengths, single-cell sequencing, and spatial omics. With this, MGI solidifies its position as a life science technology provider to offer the most extensive multi-omics solutions available today,” said Yu at the launch ceremony yesterday. 

Leveraging its robust design improvements, CycloneSEQ™ has demonstrated competitive advantages in sequencing performance, bringing further flexibility and diversity to MGI’s comprehensive range of life science research tools.

Based on this state-of-the-art technology, the new launched CycloneSEQ-WT02 and CycloneSEQ-WY01 sequencers have achieved significant breakthrough in throughput, accuracy, applications and flow cell design by building an optimal combination of patterns, demonstrating great potential in a variety of applications, including public health, genetic screening, reproductive health, environmental research, cancer research, genomics education, agri-genomics research and epigenomics research. 

CycloneSEQ-WT02 nanopore gene sequencer features a dual flow cell architecture, allowing for simultaneous independent operation. With the capacity to support fast coverage, swift sequencing, flexible testing and real-time analysis, CycloneSEQ-WT02 significantly shorten sequencing turnaround time, effectively overcoming the challenges of complex sequences. It has been successfully applied in a variety of scenarios, including the detection of complex genetic diseases such as thalassemia, generating telomere-to-telomere (T2T) genome maps for small animals, deep-sea in situ exploration, rapid identification of clinical respiratory pathogens, and de novo genome assembly.

CycloneSEQ-WY01 is a high-throughput nanopore gene sequencer. It features a high-density flow cell and ultra-high throughput capabilities, enabling ultra-long read lengths, real-time sequencing, and continuous testing.

CycloneSEQ-WT02 sequencer will be open for order in select countries later this year through MGI’s commercial channel, and CycloneSEQ-WY01 is slated for available in H1, 2025. 

With the latest sequencers added to robust lineup, MGI is now equipped to deliver a full-spectrum of sequencing technologies and a comprehensive product portfolio. This expansion fully embodies MGI’s “SEQ ALL” approach, a term showcasing its capability in providing global users with a comprehensive toolkit for multi-omics research across various throughput, read length and applications.